MANAGEMENT OF PERITONEAL CARCINOMATOSIS OF COLORECTAL ORIGIN AND REALITY IN PANAMA

Abstract

ABSTRACT

Background: The term peritoneal carcinomatosis was first used by Sampson in 1931 to describe the peritoneal spread of an advanced ovarian neoplasm. Today the term peritoneal carcinomatosis includes any tumor spread, local or massive, involving the peritoneal serosa and neighboring anatomical structures. About 30% to 40% of patients with colorectal carcinoma will develop metastases at some point, that is 90 patients. In fact, peritoneal carcinomatosis is the second most common presentation of distant metastasis from colon cancer.

Objective: To present the published evidence on the approach and surgical treatment of peritoneal carcinomatosis of colorectal cancer in other latitudes and how its implementation could improve the quality of life of these patients in Panama. As well as to promote the study, management and diffusion of the knowledge of the peritoneal metastasis mainly at national level

Design: We used scientific articles published between 2010 and 2020, which were selected for their relevance, validity and quality of content, such as those available at the National Center for Biotechnology Information, Surgical Oncology Clinics of North America, Annals of Surgical Oncology, World Journal of Surgical Oncology obtained through various virtual libraries.

Conclusion: Cytoreductive surgery in combination with intraperitoneal hyperthermic chemotherapy has improved overall 5-year survival by 40 to 51% with promising results in highly selected patients and is even considered the only potentially curative treatment.

Keywords: peritoneal carcinomatosis, colorectal cancer, cytoreductive surgery (CRS), hyperthermic intraperitoneal chemotherapy (HIPEC).