NEITHER GONE NOR FORGOTEN: LEPROSY, A CURRENT NEGLECTED TROPICAL DISEASE
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Abstract
Leprosy is a chronic granulomatous caused by M. leprae and M. lepromatosi, affecting the skin and peripheral nerves. In addition to humans it causes infection Dasypus novemcinctus and other mammals, highlighting its potential zoonotic and anthroponotic relationship.
It is a neglected tropical disease that still affects millions of people worldwide including case reports from Panama. Despite international eradication campaigns, this has not been possible, and there are still questions about transmission dynamics, as well as the role of natural reservoirs in the persistence of this disease.
The diagnostic techniques that we continue to use are the same as 100 years ago and the treatment consists of polychemotherapy with various antibiotics that act at different levels of the Mycobacterium. Although progress has been made in treatment schemes, the cure rate is not 100% and there are reports of the emergence of antimicrobial resistance.
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